We're pleased to announce the first release candidate for QuPath v0.6.0!

This is a preview version for testing. We plan to have the final release in October 2024.

If you try it out and find problems, please let us know via GitHub or the user forum.

There may be bugs!
Please don't use v0.6.0-rc1 for important work, and make sure you back up any projects that you open with it.
It is not recommended to switch between v0.5.x and v0.6.0-rc1 for the same project.

Highlights

There are lots of small and not-so-small changes listed in the Changelog.

But perhaps the biggest is that this release candidate introduces the QuPath InstanSeg extension to the world.

InstanSeg is a new, deep learning-based method for nucleus & cell segmentation that aims to be fast, accurate & easy to use.

We're working on more documentation, but for now see the extension repository for more info & links to two preprints that explain the method - both for brightfield and multiplexed images.

Note: Other extensions (e.g. for StarDist) have not been updated for compatibility with this release candidate.
We plan to update them for the final release.

What to download

• For Windows (two options, functionally the same)
  • QuPath-v0.6.0-rc1-Windows.msi - if you want a standard Windows (local) installer
  • QuPath-v0.6.0-rc1-Windows.zip - unzip it and double-click QuPath-v0.6.0-rc1.exe (no further installation needed)
• For Mac (two options, depending upon processor)
  • QuPath-v0.6.0-rc1-Mac-x64.pkg - for Macs with Intel Processors or Apple Silicon (M1/M2)
  • QuPath-v0.6.0-rc1-Mac-arm64.pkg - for Macs using Apple Silicon. This runs faster & is recommended for most users, but lacks support for a small number of file formats through Bio-Formats (particularly .czi with jpeg-xr compression).
    • To install: right-click and choose Open to install.
• For Linux
  • QuPath-v0.6.0-rc1-Linux.tar.xz - use chmod u+x /path/to/QuPath/bin/QuPath to make the launcher executable.