The need here is to be able to execute the setDomains command in the Matomo tags.
I am not sure if this should be available in the Matomo Configuration variable or if it is something you should set on the Event / Pageview level

This is what we want to be able to do:
// Tell Matomo the website domain so that clicks on these domains are not tracked as 'Outlinks'
_paq.push(['setDomains', '*.example.com']);
_paq.push(['trackPageView']);